Judy Riffle, Ph.D., Professor, Department of Chemistry; Director, Macromolecular Science and Engineering graduate program, Virginia Polytechnic Institute and State UniversityMarch 16, 2006 11:00 a.m. University Hospital Amphitheater UNH 4208
Magnetic particles that display high saturation magnetization and high magnetic susceptibility are desirable for many applications in biotechnology. Examples under current investigation include particles for cell and other molecular separations, contrast agents for MRI, field-induced tumor hyperthermia, target nanoparticles for magnetic biochip sensors, and in our case, hydrophobic magnetic fluids for treating retinal detachment. For all of these applications, it is desirable to understand how to control dispersion and aggregation of magnetic nanoparticles by applying uniform or gradient magnetic fields. The vast majority of magnetic biomaterials have involved iron oxides due to their oxidative stability and biological compatibility. This lecture will address the design of both hydrophilic and hydrophobic magnetic nanoparticle structures.
Vladimir Tsukruk, Ph.D., Professor, Department of Materials Science and Engineering, Iowa State UniversityNovember 17, 2005 12:00 p.m. Bennett Hall 2020
We discuss recent results obtained in our group on assembling of freely standing membranes from ultrathin multilayered polymer-nanoparticle films (1). These films obtained via layer-by-layer assembly from oppositely charged polyelectrolytes and gold nanoparticles showed outstanding micromechanical behavior and high sensitivity to external pressure and temperature. Optical properties of arrays of membranes have been studied and these arrays are suggested as a prospective platform for acoustic, thermal, and chemical sensing as well as programmable storages for nanoscale fluidic.
Howard E. Gendelman, M.D., Professor and Chair, Department of Pharmacology and Experimental Neuroscience, Larson Professor of Internal Medicine; Director, Center for Neurovirology and Neurodegenerative Disorders, UNMCMay 19, 2005 11:00 a.m., Eppley Science Hall Amphitheater
Tatsuro Ouchi, Ph.D., Professor, Department of Applied Chemistry, Faculty of Engineering, Kansai University, Suita, Osaka, JapanAugust 11, 2004 10:00 a.m., Durham Research Center, Room 1004
Kam W. Leong, Ph.D., Professor, Department of Biomedical Engineering, School of Medicine, The Johns Hopkins UniversityApril 21, 2005 11:00 a.m., Eppley Science Hall Amphitheater
Alexei A. Bogdanov, Jr., Ph.D., Associate Professor of Radiology/Chemistry, Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical SchoolMarch, 17, 2005 11:00 a.m., Eppley Science Hall Amphitheater
Allan S. Hoffman, Ph.D., Professor of Chemical Engineering and Bioengineering, Department of Bioengineering, University of WashingtonFebruary 17, 2005 11:00 a.m., Eppley Science Hall Amphitheater
Vladimir P. Torchilin, Ph.D., Distinguished Professor of Pharmaceutical Sciences, Chair, Department of Pharmaceutical Sciences,Director, Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern UniversityFebruary 16, 2006, 11:00 a.m. University Hospital Amphitheater UNH 4208
Ideally, drug carrier should be able: (a) to accumulate in required organ or tissue, and then (b) penetrate inside target cells delivering there its load (drug or DNA). To be able to behave this way, drug carrier should simultaneously carry on its surface various moieties capable of functioning in a certain orchestrated order. Currently, nanoparticulate delivery systems are built simultaneously capable of longevity and target recognition. In general, many other "useful" moieties can be attached to the drug carrier surface, such as diagnostic/imaging groups, cell penetrating peptide groups, stimuli-sensitive groups capable of releasing the drug under certain conditions, etc. One can think about the development of multifunctional drug delivery systems(long-circulating, specifically targeted, and capable of cell penetration) built in such a way that their certain functions may switch on and switch off under the action of specific conditions (pH, temperature) characteristic of pathological zone. Contrast/reporter group associated with such carriers can provide additional scientific or diagnostic information. Various multifunctional nanocarriers will be described for targeted drug delivery to and into various pathological cells and tissues using cancer and myocardial infarction as examples.
David Oupicky, Ph.D., professor and Parke-Davis Chair in Pharmaceutics for the UNMC College of Pharmacy, will receive the Outstanding Mentor of Graduate Students at the annual Faculty Sen...
Eight UNMC students and one UNO student attended the 12th annual International Student Research Forum hosted by Griffith University in ...
Spring break conjures up images of sunny beaches and a warm surf, but for four first-year UNMC medical students it was a mission trip t...