986025 Nebraska Medical Center Omaha, NE 68198-6025
Professor, College of Pharmacy, Department of Pharmaceutical Sciences
University of Nebraska Medical Center
Nanoscale Structure, Dynamics and Interactions - Seeing and Manipulating Biomolecules
The main objective of research projects in the Genomics area is to unravel the role of the DNA dynamics at different levels as key mechanisms for various DNA functions including gene regulation, DNA recombination and the mismatch repair with the major focus on DNA recombination. We utilize single molecule imaging approaches such as fluorescence and AFM to directly detect and analyze the DNA strand exchange process at the base pair accuracy.